LGALS3 and stroke disorder: Related to the neuroinflammatory response during stroke, Tomas Deierborg’s group demonstrated in an in vivo stroke model the deleterious role of gal-3 dependent inflammatory response, in which the lack of gal-3 reduced the infarct area in the stroke-induced model, and intranigral injection of LPS in gal-3 knock-out mice reduced neuronal death compared to gal-3 WT mice [722].