Therewith, it will be interesting to test the potential role of CD16a-associated ADCC for NK cells of both origins (UC-NK cells, P-NK cells) against a Her2/Neu breast cancer cell line or other tumor cell lines (e.g., melanoma, colon cancer cell lines) in the presence of trastuzumab or equivalent drugs in future. The gene discussed is ERBB2; the disease is colonic neoplasm.