Decreased LINC00240 and Nrf2 levels and increased miR-155 level were also observed in placenta tissues from the preeclampsia model, and further overexpression of LINC00240 reversed all the changes on LINC00240, miR-155 and Nrf2 expression levels (Fig. 7J, K). This evidence concerns the gene NFE2L2 and preeclampsia.