HOTAIRM1 and neoplasm: After overexpression of HOTAIRM1, the invasion and migration of tumor cells were significantly improved, but after transfection of miR-328-5p simulant, the effect of HOTAIRM1 was weakened (Fig. 4A, C), and The overexpression efficiency of HOTAIRM1 and miR-328-5p was also verified (Fig. 4B).