PDLIM2 and Alzheimer disease: Although the larger number of DMPs identified in the DLPFC is consistent with the more advanced levels of AD pathology in this brain region compared to the OCC1,2,24, effect sizes were strongly concordant across regions (Supplementary Figs. S14 and S15) with one DMP (cg18100976, annotated to PDLIM2) being identified in both the DLPFC and OCC.