SOX10 and Alzheimer disease: Third, we characterized genome-wide patterns of DNA methylation in NeuN+ (neuronal-enriched), SOX10+ (oligodendrocyte-enriched), and NeuN–/SOX10– (microglia- and astrocyte-enriched) nuclei populations from a subset of BDR donors, exploring the extent to which AD-associated cortical differences in DNA methylation are driven by changes within specific cell populations.