Overall, effect sizes for the 67 AD pathology DMPs were found to be highly consistent between analyses of the AD (Braak NFT stage, CERAD score, Thal phase) and non-AD (Braak LB stage and TDP-43 status) neuropathology measures (see Supplementary Fig. S12) suggesting consistent effects across each type of neuropathology or that these effects are driven by underlying disease (i.e., a consequence rather than directly related to neuropathology). The gene discussed is TARDBP; the disease is Alzheimer disease.