Results revealed no significant association between AKT1-rs10138227 and BC at a genotypic or allelic level when analysed using both the 1000 Genomes Project data (genotype: p = 0.062; allele: p = 0.678) and gnomAD (genotype: p = 0.132; allele: p = 0.913). This evidence concerns the gene AKT1 and breast cancer.