Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis showed that the high UNG expression group was enriched in several tumor-related pathways, such as p53 signaling pathway, TNF signaling pathway, DNA replication, focal adhesion, NF-kB signaling pathway, and Human T-cell leukemia virus 1 infection (Supplementary Figure 3B). Here, TNF is linked to neoplasm.