However, unbiased screening with intracellular expression fragments covering SARS-CoV-2 identified each of the epitopes HLA-A*02:01/ALWEIQQVV and HLA-A*01:01/CTDDNALAYY among the three most frequently detected CD8 T cell responses for their HLA restriction65, consistent with a significant role of these epitopes and the non-structural proteins nsp8 and nsp9 in T cell control of infection. The gene discussed is CD8A; the disease is infection.