When these SAEC were divided into two groups according to sex of the cell donors, only a significant difference was observed between the two subgroups in the expression of TMPRSS2, with female SAEC showing significantly higher expression than male SAEC (Figure 4B), while comparing of the four genes in patients with or without hypertension no significant differences could be observed (Figure 4C). The gene discussed is TMPRSS2; the disease is Hypertension.