INS and type 2 diabetes mellitus: There is a wealth of data on the preventive or delaying effect of physical activity against type II diabetes (Thomas et al., 2006; World Health Organization 2011; Smith et al., 2016), and a wealth of data is available on the molecular mechanism underpinning exercise- and insulin-induced glucose uptake and its relation to type II diabetes (Stanford and Goodear, 2014; Carson 2017).