CLP induced the expansion of the TN, TCM, and TVM subpopulations (Figure 7A) and an increased expression of CD69 on TN and TVM cells (Figure 7B) in the BM of TLR2−/− mice in a similar pattern as observed for WT mice (Figures 4B, D), which argues against a role of TLR2 in the activation of CD8 T cells during sepsis. The gene discussed is TLR2; the disease is Sepsis.