Meanwhile, combining pGSN with IL-6 (AUC=0.904; p=0.003) showed a more significant ability to predict mild COVID-19 and IP-10 (AUC=0.754; p=0.065), HGF (AUC=0.746; p=0.075) and TGF-β1 (AUC=0.765; p=0.078) demonstrated a trend toward significance (Figure 5A;Supplementary Figure S4C). The gene discussed is IL6; the disease is COVID-19.