Dysregulation of IL-10 has shown to be linked with susceptibility to numerous infectious diseases such as Mycobacterium avium Infection (45), Helicobacter hepaticus-induced colitis (46), HIV (47), hepatitis C virus (HCV) infection (48) and autoimmune diseases like inflammatory bowel disease (39, 49). The gene discussed is IL10; the disease is Mycobacterium avium complex disease.