Of the separate three markers, the density of tumor-infiltrating CD3(+) cells in pNLR-low group was significantly higher than that in pNLR-high group (Mann Whitney U test, p = 0.008), while no significant differences were found between pNLR-high and pNLR-low group of CD11b(+) or CD19(+) cell density (Mann Whitney U test, p = 0.330, 0.895, respectively) (Figure 6A). This evidence concerns the gene ITGAM and neoplasm.