TRDMT1 and cancer: In our analyses, we discovered that ARPC5 expression was correlated with the expression of four methyltransferases (DNMT1, TRDMT1, DNMT3A, and DNMT3B) in multiple tumors, such as BRCA, LGG, KICH, LIHC, SKCM, THYM, and UVM (Figure 9D), whereas DNMT3L was evidently correlated with ARPC5 expression only in five cancer types: BRCA, LGG, LIHC, TGCT, and THCA.