VEGFA and abdominal aortic aneurysm: In abdominal aortic aneurysm induced by Angiotensin II infusion in apolipoprotein mice, the treatment with empagliflozin inhibited leukocyte-endothelial cell interactions, macrophages infiltration, and secretion of pro-inflammatory markers such as chemokine (C-C motif) ligand 2 (CCL-2), CCL-5, Vascular Endothelial Growth Factor (VEGF), MMP-2, MMP-9, p38 mitogen-activated protein kinase (MAPK), and NF-kB (62).