The inhibition of TGF-β1-induced Collagen-1, α1 chain (COLIα1), as well as α-SMA by TSA, was significantly reduced when the BMP-7 receptor inhibitor dorsomorphin was administered, suggesting that the HDAC inhibitor TSA counteracted TGF-β1-induced renal fibrosis by upregulating the transcription of BMP-7 (Manson et al., 2014). This evidence concerns the gene BMP7 and renal fibrosis.