Given its strong correlation with PCa and the possibility of isolating prostate cells or nucleic acids with the mutation on urine samples, T2:ERG has been proposed as a biomarker for PCa with rather low SE, 37%, but high SP, 93%, and PPV, 94% in post- digital rectal examination (DRE) urine specimens (33, 34). The gene discussed is ERG; the disease is posterior cortical atrophy.