The expression of these genes in gastric cancer tissues was further evaluated in the GEO database (GSE 27342), which found that the levels of MYOF (P<0.0001), ANXA2 (P<0.0001) and ITPRIPL2 (P<0.001) mRNAs were significantly higher, and the levels of LEPROT (P<0.001) and AHNAK (P<0.05) mRNAs significantly lower, in gastric cancer than in normal gastric tissue samples, with no significant difference in CLIP1 mRNA expression (P>0.05; Figure 1H). The gene discussed is ITPRIPL2; the disease is gastric cancer.