ACADSB and 2-methylbutyryl-CoA dehydrogenase deficiency: Short/branched-chain acyl-CoA dehydrogenase (SBCAD) deficiency (SBCADD) (OMIM# 600301, also known as 2-methylbutyrylglycinuria, OMIM#610006) is an autosomal recessive metabolic disorder due to mutations in the ACADSB gene (1, 2).