Other studies have linked ferroptosis to NB, for example, lacking ferritin heavy chain, Erastin, or RSL3 could induce ferroptosis cell death in NB N2A cells (Lu et al., 2021), but it is unclear whether some genes that regulate ferroptosis, such as TP53 (Leu et al., 2020) and BRD4 (Sui et al., 2019), are associated with NB patient prognosis. The gene discussed is TP53; the disease is neuroblastoma.