In contrast, some studies suggested that CAV1 was overexpressed in bladder, esophagus, lung, and prostate carcinomas (Yang et al., 1998; Yang et al., 1999; Ho et al., 2002; Kato et al., 2002; Yoo et al., 2003), and CAV1 upregulation could promote the proliferation, invasion, and distant metastatic potential of cancer cells (Joshi et al., 2008; Tanase et al., 2009; Martinez-Outschoorn et al., 2015). This evidence concerns the gene CAV1 and prostate carcinoma.