VPS13A and nervous system disorder: Loss of function mutations in VPS13A have been linked to choreaacanthocytosis, a neurological disorder that leads to Huntington-like muscledegeneration and abnormally shaped red blood cells (Rampoldi et al., 2001; Ueno et al., 2001), whilemutations in VPS13C are associated with early onset Parkinson's disease (Lesage et al., 2016).VPS13A is found at ER-mitochondria contact sites, whereas VPS13C localizes toER-late endosome/lysosome contact sites (Kumar et al., 2018).