HP and obesity due to melanocortin 4 receptor deficiency: Notwithstanding, in the adjusted regression, only obesity (only adjusted for age and gender, OR 8.103 p=0.003), segmented neutrophils (OR 1.303, p=0.010), lymphocytes (OR 0.726, p=0.013), Sa/FiO2 (OR 0.987, p=0.025) and zonulin levels (OR 2.666, p=0.007) remained significant after adjustment for age, gender, and obesity (Table 4).