As we did not find a previously published systematic approach for gene-disease classification for NSHL, we applied an existing framework proposed by ClinGen and observed that half (21/42) of the genes were associated with AD NSHL, and more than one-third (23/65) of AR genes, half (3/6) of X-linked genes, and one-fourth (4/16) of all forms of the eight AR/AD genes exhibited limited gene-disease association. The gene discussed is AR; the disease is Alzheimer disease.