OTOA and nodular sclerosis classical Hodgkin lymphoma: The second-most recurrent pathogenic CNV was a microdeletion of approximately 244.2 Kb present in heterozygosity in four individuals (AF = 0.095%) involving the OTOA gene (associated with the AR form of NSHL) and the surrounding METTL9 gene (not associated with any Mendelian disorder in OMIM).