PPARA and metabolic dysfunction-associated steatotic liver disease: And the top 10 significantly downregulated pathways were the peroxisome proliferator-activated receptor (PPAR) signaling pathway, Non-alcoholic fatty liver disease (NAFLD), Peroxisome, Propanoate metabolism, Fatty acid metabolism, Carbon metabolism, Alzheimer’s disease, Parkinson’s disease, Oxidative phosphorylation, and Citrate cycle (TCA cycle) (Figure 2E).