Furthermore, the expression levels of RPS27A, MAPK1, STAT1, TLR4, RPS6, FBL, RPS3, RPS2, and GART are positively correlated with the blood vessel remodeling genes (Table 6), indicating that these genes are critically regulating the vasculature in PAH. This evidence concerns the gene MAPK1 and pulmonary arterial hypertension.