Furthermore, the expression levels of RPS27A, MAPK1, STAT1, TLR4, RPS6, FBL, RPS3, RPS2, and GART are positively correlated with the blood vessel remodeling genes (Table 6), indicating that these genes are critically regulating the vasculature in PAH. The gene discussed is RPS3; the disease is pulmonary arterial hypertension.