CD274 and cancer: The up-regulated KEGG pathways are significantly involved with immune regulation signaling, including Toll-like receptor signaling pathway, adipocytokine signaling pathway, Fc gamma R-mediated phagocytosis, Vibrio cholerae infection, NOD-like receptor signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, and RIG-I-like receptor signaling pathway, PPAR signaling pathway.