In order to further characterize how concomitant deletion of Csf1r affects transcriptome changes induced by loss of Mir34a in adenomas, we determined which Mir34a targets may be coordinately regulated by both Mir34a and STAT3, AP1 (JUN:FOS) and SRF (Fig. 8) in a coherent feed-forward manner (hereafter referred to as “Mir34a/TF targets”). The gene discussed is MIR34A; the disease is adenoma.