SNHG16 knockdown inhibited the colony formation (Fig. 3E), proliferation (Fig. S2B), migration (Fig. 3E and Fig. S2C), and invasion (Fig. 3E) of CRC cells, and YAP1 overexpression rescued the effect of SNHG16 knockdown on tumor progression. The gene discussed is SNHG16; the disease is colorectal carcinoma.