Three stable cell lines HCT116 Lv-anti-SNHG16 NC, HCT116 Lv-anti-SNHG16 + Lv-Oe-YAP1 NC, and HCT116 Lv-anti-SNHG16 + Lv-Oe-YAP1 were separately injected into the tail vein of mice to confirm the effect of SNHG16 on tumor metastasis. Here, YAP1 is linked to neoplasm.