MMP1 and malignant colon neoplasm: Based on the above research, this study proposed the hypothesis of the biological effects of MMP1, 2, and 9 on colon cancer; jointly screened the monomer Chinese medicine component kaempferol through bioinformatics and traditional Chinese medicine database (https://www.herb.com); and jointly tested the previous hypothesis through HCT116 and HT29 colon cancer cells, thus strongly proving that MMP1, 2, and 9 can affect the occurrence and development of colon cancer cells.