Compared with the HG group, the protein levels of Beclin1, Atg7, FoxO1, and LC3 II/LC3 I was significantly increased (p < 0.05 and p < 0.01), and the expression of p-FoxO1 was significantly decreased (p < 0.05) in the HG + DS group. The gene discussed is BECN1; the disease is Dravet syndrome.