BAD and infection: Indeed, following infection of Vero76 cells with TCRV, we were able to confirm the phosphorylation of the tumor suppressor protein p53 (at Serine 392) and the BH3-only factor Bad (at Serine 112), both of which become prominent at day 4 pi, which is also consistent with the kinetics of caspase 3 cleavage in response to infection (Figure 1a).