It is noteworthy that Snail2 was also strongly regulated during HCMV infection (Figure 2), and as Snail2–Snail1 interactions have been described to cooperatively influence the VDR [44], it remains to be determined whether very early Snail2-mediated repression events during infection can trigger the epigenetic changes for VDR/Snail1 dysregulation via interconnected feedback loops. Here, VDR is linked to infection.