After HLJ/18-7GD immunization, however, the levels of GM-CSF, IFN-γ, and TNF-α were significantly upregulated (p < 0.01) at 7 DPI and returned to the pre-immunization level or lower than the minimum detectable concentration, which was in contrast to the results obtained after HLJ/18 or HLJ/18ΔCD2v infection. The gene discussed is IFNG; the disease is infection.