Moreover, over a 35-day post-injection observation period, the mean tumor volume of mice treated with SG600-p53 increased 6.7-fold, to 1212 mm3, but the tumor volume in mice treated with SG635-p53 increased only 1.7-fold, to 322 mm3 (p < 0.001) [22]. This evidence concerns the gene TP53 and neoplasm.