As a step in this direction, we have, in this study, demonstrated that cellular immune responses induced by FLU-v vaccination cross-recognized all influenza strains tested (H1N1, H3N2, H5N1, H7N9, and B influenza), as measured by an increase in IFN-γ- and granzyme-B-secreting cells detected in vitro. This evidence concerns the gene IFNG and influenza.