In relation to Crohn’s disease, the LGMN gene was previously mentioned in a group of highly variable genes between resident and inflammatory macrophage clusters in a study in which the authors identified a cellular module named GIMATS, which consisted of activated dendritic cells, inflammatory macrophages, activated T cells, IgG plasma cells, activated fibroblasts and endothelial cells [32]. The gene discussed is LGMN; the disease is Crohn disease.