Experiments in nude mice-bearing human cancer xenografts demonstrated that the uptake of [99mTc]Tc-AC12-GGGC in B7-H3-positive SKOV-3 xenografts was significantly (p < 5 × 10−6) higher than in B7-H3-negative Ramos xenografts 4 h after injection (Figure 8), which supports that the tumour accumulation was B7-H3-specific in vivo. The gene discussed is CD276; the disease is cancer.