CD276 and neoplasm: In a previous study [27], an anti-B7-H3 humanized monoclonal antibody labelled with zirconium-89 (89Zr-DS-5573a) was used for preclinical imaging of B7-H3 in MDA-MB-231 tumours, and showed a high tumour uptake (4.58 ± 0.69 %ID/g), with normal tissues demonstrating clearance patterns typical of a radiolabelled intact humanized antibody.