Estrogen receptor-positive (ER+) breast cancer is the most common type of progressive breast cancer in women, and its progression is facilitated by the estrogen hormone which regulates the levels of cyclin D1, Bcl-2, Myc, and VEGF, all of which are required for cell cycle, cell survival, and angiogenesis stimulation [2,3]. This evidence concerns the gene CCND1 and breast cancer.