Oncolytic adenovirus that was loaded with IL-7 combined with B7H3-targeted CAR-T therapy enhanced T-cell proliferation, increased tumor-infiltrating B7H3-CAR-T-cells, and extended the survival of mice bearing GL161 tumours, despite failing to reverse the exhaustion of B7H3-CAR-T-cells [234]. The gene discussed is IL7; the disease is neoplasm.