RAC2 and pancreatic adenocarcinoma: For example, eIF4A-dependent mRNAs, including critical Kirsten rat sarcoma virus (KRAS) signaling molecules, such as phosphoinositide 3-kinase (PI3K), Ras-related protein (RalA), Ras-related C3 botulinum toxin substrate 2 (Rac2) and MYC, were identified in pancreatic adenocarcinoma by transcriptome-scale ribosome footprinting [42].