SSTR2 and neoplasm: In humans, as an amino acid solution containing arginine and lysine is used to saturate these renal receptors, the renal uptake and potential renal toxicity of radiopharmaceuticals is limited, as noted in several clinical studies of [177Lu]Lu-satoreotide tetraxetan [5,6,20].The low toxicity induced by both agonist and antagonist products could be due to the high SST2 expression in AR42J cells and a potential sink effect in the tumour limiting the radioactivity uptake in other organs.