The TNF-α, IL-6, and IL-1β mRNA expression levels were measured in the HFCD-induced atherosclerosis CON group compared with those of the NOM group, while the mRNA expression level of IL-6, IL-1β, and TNF-α decreased in the GPE treated group (p < 0.05), and some of the inflammatory cytokines reached the average level. This evidence concerns the gene IL1B and atherosclerosis.