, MIS > 5 points, PA ≤ 4°, s-prealbumin ≤ 30 mg/dL, and the lowest gender-adjusted HGS cut-off point using right-HGS were predictors of mortality in patients with stage 3b, 4–5 CKD, as shown in Figure 2 and Figure 3. The gene discussed is TTR; the disease is chronic kidney disease.