We hypothesize that (1) mean serum albumin, weight, body mass index (BMI) and GNRI scores at the time of diagnosis will be lower in the short-term survival group compared to the longer-term survival group, (2) weight, albumin levels, mean BMI and BMI categories will be positively associated with survival and (3) patients at nutritional risk based on the GNRI score will have shorter overall survival compared to those at no nutritional risk among patients with advanced pancreatic cancer. This evidence concerns the gene ALB and familial pancreatic carcinoma.