FGF23 and obesity due to melanocortin 4 receptor deficiency: Our findings concur with several studies performed in adults and adolescents without chronic kidney diseases (CKD), which demonstrated that FGF-23 was significantly higher in overweight and obese subjects (especially those with visceral obesity), and correlated positively with markers of obesity (BMI, WC, WHR, visceral fat mass and subcutaneous fat area) [45,46,47,48].