The plant’s beneficial effect was investigated using an ethanol-induced gastric model, which stimulated ulcers through a variety of mechanisms such as free radicals OH, NO production, mucus exhaustion, mucosal damage, and the release of superoxide anion, which ultimately prolonged tissue oxidative stress and numerous studies have suggested that pro-inflammatory mediators such as interleukin-8 (IL-8), TNF-α as well as COX-2 upregulation and p-NF-ƙB activation, play a role in inflammatory cascades [24,26]. This evidence concerns the gene TNF and ulcer disease.