Despite the large number of studies, most research shows that these polysaccharides have anti-gastric cancer effects that regulate different signal pathways, including the inhibition of the TGF-β, AKT/PI3K, IGF/IR, and Wnt/β-catenin signaling pathways, and activate the MAPK and Fas/FasL signaling pathways (Figure 3). The gene discussed is TGFB1; the disease is gastric cancer.