As Tregs suppress Th17 inflammation and secrete IL-10 and transforming growth factor-β (TGF-β1) to induce immunotolerance [8,9,10], the administration of Treg-inducing strains and fecal microbiota transplantation have been developed to rehabilitate IBD [10,11,12]. The gene discussed is TGFB1; the disease is inflammatory bowel disease.