ABCB1 and type 2 diabetes mellitus: Therefore, this study aimed to investigate the relationship between rs4148727 T2DM and lipid profiles (i.e., apolipoprotein B (APO-B), apolipoprotein A (APO-A), high-density lipoprotein (HDL) cholesterol (HDL-C), LDL cholesterol (LDL-C), total triglycerides (TG), and total cholesterol (TC)) in Chinese families, to explain ABCB1’s pleiotropic genetic effect.